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- The Facts:
New research is showing that TRPV1, a cannabinoid receptor found abundantly in the heart may be key in slowing down and potentially even reversing heart failure.
- Reflect On:
With so many medical applications and the potential to treat and even cure a wide variety of diseases, why has there been such a lack of research, funding and clinical trials when it comes to medical marijuana?
Cannabis could potentially slow and even reverse heart failure via TRPV1, a cannabinoid receptor. This is according to research led by a team at the University of Hawaiʻi John A. Burns School of Medicine (JABSOM). Alexander Stokes, a JABSOM assistant professor in cell and molecular biology, said “the potential medical benefits of using cannabis-based therapies for the treatment of heart disease are promising.”
TRPV1 is showing long-term effective reversal of heart failure when the substance is administered orally. The key here is orally, this doesn’t mean that you can smoke cannabis and it will be good for your heart, in fact, it may very well have a negative effect if you do that. “TRPV1 has primarily been studied as a pain receptor,” said Stokes. “The receptors are abundant in the heart, and we are excited to show that if we inhibit its function with oral doses of drugs, we can reverse some effects of heart failure.”
The findings were published in the journal Channels.
A Big Topic Right Now
The topic of medical marijuana is a big one right now, especially in Canada where it was recently legalized. For years, there’s been a negative stigma attached to the substance, and when one dives deep into the subject it’s quite easy to see why. Cannabis, often called marijuana, has potential to treat and possibly even cure a wide range of diseases, but because of prohibition, the studies examining the medicinal aspects of the herb have been very limited. This is very unfortunate, for a number of reasons, and also very suspicious.
If we look at cancer, for example, multiple studies have clearly shown its potential to completely destroy cancer cells, many in vitro studies have clearly demonstrated this potential, without question. They’re not hard to find and have been published in abundance. Here is a video of Dr. Christina Sanchez, a molecular biologist at Compultense University in Madrid, Spain, explaining how THC (the main psychoactive constituent of the cannabis plant) can completely kill cancer cells. THC is simply one constituent of cannabis. It has been shown to be effective for multiple diseases as well, while other diseases are better treated with CBD, another constituent within cannabis. This begs the question, why have there been no, or at least so few, clinical trials set up as a result?
This hasn’t stopped people taking matters into their own hands though. There are numerous examples all over the internet of people claiming that cannabis oil, for example, cured their cancer. But from a scientific perspective this isn’t evidence, it’s simply anecdotal and as a result of a lack of research we cannot officially say cannabis kills cancer. We can only say that it has tremendous potential and that a lot more research is needed.
Pharma vs Cannabis
When a pharmaceutical drug shows even less than half of the potential that marijuana has shown, clinical trials are set up right away. Just imagine if the same resources that are poured into conventional cancer treatments were given to medical marijuana’s potential to treat cancer, among a wide range of other diseases. If that were to happen, we would know much more. But the lack of research continues. Is it because if scientists were to discover what strain, method of delivery and all of the other factors that require more research that are needed to treat disease, cannabis could become an effective treatment for cancer? What would happen to conventional treatments? Would people have to pay for their treatment if it was disclosed how to, for example, make cannabis oil in the right way for a specific cancer? Maybe this has something to do with it?
Big pharma would lose billions. It’s definitely something to think about.
What’s happening right now with the legalization of marijuana is that components of it are allowed to be studied. It seems that drugs will be developed to synthesize certain components of the plant, and the drugs themselves can then be patented. This is how big pharma will ultimately make money off of medical marijuana.
The Challenge With Government Control Of Cannabis
It’s great to see people with Parkinson’s, Dementia, Alzheimer’s disease, Epilepsy, cancer and more have tremendous success with medical marijuana. What’s unfortunate is that mainstream medical marijuana will be in the hands of big pharma, it already is. We will not know how it’s grown, how it’s been manipulated, and what’s been changed. It’s simply being used for profit, because at the end of the day that’s what it’s all about in our current infrastructure. We have a sick care industry, not a health care industry.
A free, open and caring society, a health care industry that truly cares about health could use multiple natural substances to completely wipe out the need for any pharmaceutical drug. There are massive amounts of foods, herbs and plants that, if studied in full, could completely eliminate our dependence on the corporation.
“The medical profession is being bought by the pharmaceutical industry, not only in terms of the practice of medicine, but also in terms of teaching and research. The academic institutions of this country are allowing themselves to be the paid agents of the pharmaceutical industry. I think it’s disgraceful.”
– Arnold Seymour Relman (1923-2014), Harvard professor of medicine and former Editor-in-Chief of The New England Medical Journal (source)
Important Thoughts To Consider About Cannabis
The other side of the coin is that heavy cannabis use, although not lethal, can be dangerous and potentially damaging to young brains that are not fully developed, and perhaps to those who use it on a regular basis in ways we do not yet understand.
It’s not as harmful as alcohol abuse or smoking cigarettes, but there is still a lot that we don’t know. Legalization in Canada at least have led to the idea that it’s completely safe and beneficial for everybody. This is also, most likely, not true. We need to get past the idea that it’s something healthy for everybody, and even healthy to smoke cannabis on a regular basis. But when it comes to the medicinal aspects of cannabis, for several diseases, there is a very serious discussion to be had here as it’s again, already helping many people around the world with their cancer, with their epilepsy, etc.
With many people losing trust in the medical industry, it’s easy to see why they are turning to growing their own cannabis, testing doses, and methods of delivery, etc. For some, it’s a shot in the dark but worth a try.
We are not advocating that it’s healthy to use cannabis recreationally and that it will not have any negative effects, we are simply stating that it’s a head scratcher how such a potent medical plant that clearly has multiple medical applications has been ignored and prohibited from research and professionally treating many diseases with it.
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